CATHEPSIN S DEFICIENCY RESULTS IN ABNORMAL ACCUMULATION OF AUTOPHAGOSOME IN MACROPHAGES AND ENHANCES

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：hmxxg

【摘要】

：

Objectives Understanding the mechanisms of fibrosis development in the heart during hypertension is pivotal to find new therapies to counteract heart failure.In

【作者】

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Pan Lili Yulin Li Lixin Jia Yanwen Qin Yongfen Qi Huihua Li Jie Du

【机构】

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BeijingAnzhenHospital,TheKeyLaboratoryofRemodelling-RelatedCardiovascularDiseases,CapitalMedicalUniv

【出处】

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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

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2013年10期

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Objectives Understanding the mechanisms of fibrosis development in the heart during hypertension is pivotal to find new therapies to counteract heart failure.In this study, we aimed to define the role of Cathepsin S (Cat S) in the development of cardiac inflammation and fibrosis induced by angiotensin Ⅱ (Ang Ⅱ).

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CATHEPSIN S DEFICIENCY RESULTS IN ABNORMAL ACCUMULATION OF AUTOPHAGOSOME IN MACROPHAGES AND ENHANCES

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