【摘 要】
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目的 Asthma-Chronic Obstructive Pulmonary Disease(COPD)overlap syndrome(ACOS)is a new determinate syndrome whoseexact characteristics remain unclear.The objective of this study was to find more differen
【机 构】
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Shanghai Pulmonary Hospital,Tongji University School of Medicine
【出 处】
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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议
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目的 Asthma-Chronic Obstructive Pulmonary Disease(COPD)overlap syndrome(ACOS)is a new determinate syndrome whoseexact characteristics remain unclear.The objective of this study was to find more difference between ACOS and COPD方法 Data from 65 patients with ACOS and 65 patients with COPD were retrospectively collected and analyzed.The basis of thisstudy was to compare the two groups while ruling out differences in age,sex and smoking history结果 Patients with ACOS tended to have earlier ages of onset,longer durations of symptoms,better nutritional status,highersingle-breath diffusing capacity of carbon monoxide(DLCO)％predicted and airway resistance％predicted.DLCO％predicted,airway resistance％predicted,and length of hospitalization were the variables most significantly associated with the presence ofACOS in patients with COPD.ROC correlating airway resistance％predicted value and current ACOS showed an optimal cutoff ofairway resistance％predicted of over 296.6.During follow-up,16 patient deaths were recorded(3 patients with ACOS).The riskremained significantly higher in patients with COPD alone than in patients with ACOS.
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