Synthesis of Functionalized 3-Arylpyridazines via Pd-catalyzed Decarboxylative Cross-coupling of Pyr

来源 :第十九届全国金属有机化学学术讨论会 | 被引量 : 0次 | 上传用户:man168176
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
3-Arylpyridazine is a ubiquitous structural motif found in pharmaceuticals,[1] ligands,[2] and functional materials.[3] Over the past years,the synthesis of 3-arylpyridazine derivatives has attracted a great deal of attention.
其他文献
NHC-Pd(Ⅱ)-Im complex 1 have proven an efficient catalyst in the reaction between tetralones 2 and aryl chlorides 3,giving the α-arylated tetralones 4 in good to high yields.
会议
偶联反应在构筑碳碳键以及碳杂原子键中发挥重要作用,新型高催化活性膦配体的使用促进偶联反应的高效和绿色化[1].本课题组合成了一系列茚基膦配体,此类配体与钯构成的催化剂可用于催化氯代芳烃的Suzuki,Sonogashira,Buchwald-Hartwig 等反应[2].
会议
Organic sensitizers have attracted tremendous attention of many researchers owing to their low-costs,light weight,moderate efficiency,flexibility and easy fabrication.
会议
Gene therapy with broad-spectrum,safe,specific and effective advantage compared to traditional chemical treatment.
会议
The living organisms respond differently to the enantiomers of various drugs.Irinotecan is an important candidate in the searching of anticancer drugs.
Catecholamines,such as DA,levodopa(L-DOPA),adrenaline and noradrenaline,are an important class of neurotransmitters and are involved in a variety of central nervous system functions.
会议
自然界中含量丰富的五环三萜化合物具有抗炎、抗癌、抗病毒等多种生物活性[1].基于独特的手性刚性骨架和多个可修饰位点的特点,此类化合物的聚集性质和在超分子组装方面的应用已经引起关注[2].
会议
Pillararene-based pseudo[2]rotaxanes could be achieved by pillararenes with three different types of guest molecules:(Ⅰ) electropositive guests,1(Ⅱ) neutral guests,2 and(Ⅲ) electronegative guests.
会议
Developing multifunctional gene/drug delivery systems with the merit of storage stability,low cytotoxicity,high gene/drug loading capacity,as well as controllable gene/drug releasing features,has attr
会议
Palladium-catalyzed organic reactions has emerged as one of the most powerful method of organic synthesis,in particular for carbon-carbon bond formations.
会议