The baculovirus core gene ac83 is required for nucleocapsid assembly and per os infectivity of Autog

来源 :第十届全国病毒学学术研讨会 | 被引量 : 0次 | 上传用户：zjbme2010

【摘要】

：

　　Autographa californica nucleopolyhedrovirus (AcMNPV) ac83 is a baculovirus core gene, and its function in the AcMNPV life cycle is unknown.In the present st

【作者】

：

Shimao Zhu Wei Wang Yan Wang Meijin Yuan Kai Yang

【机构】

：

StateKeyLaboratoryofBiocontrol,SunYat-senUniversity,Guangzhou510275,China

【出处】

：

第十届全国病毒学学术研讨会

【发表日期】

：

2013年9期

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　　Autographa californica nucleopolyhedrovirus (AcMNPV) ac83 is a baculovirus core gene, and its function in the AcMNPV life cycle is unknown.In the present study, an ac83-knockout AcMNPV (vAc83KO) was constructed to investigate the function of ac83 through homologous recombination in Escherichia coli.No budded virions were produced in vAc83KO-transfected Sf9 cells, although viral DNA replication was unaffected.

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The baculovirus core gene ac83 is required for nucleocapsid assembly and per os infectivity of Autog

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