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  5. Semaphorin 4D Contributes to proinflammatory of Psoriasis by Inducing Cytokine Production

Semaphorin 4D Contributes to proinflammatory of Psoriasis by Inducing Cytokine Production

来源 :Regional Meeting of International Society of Dermatology(201 | 被引量 : 0次 | 上传用户：siquan
【摘 要】
：
Background: Psoriasis is an autoimmune skin disease,in which keratinocytes play a crucial role in the pathogenesis.Semaphorin 4D(Sema4D) is an pro-inflammatory factor that has been found expressed in
【作 者】
：
Chen Zhang ChunYing Xiao Wei Li 
【机 构】
：
Department of Dermatology, Xijing Hospital, Fourth Military Medical University,Shaanxi, Xi'an, Chin
【出 处】
：
Regional Meeting of International Society of Dermatology(201
【发表日期】
：
2016年8期
【关键词】
：
Serna4D psoriasis inflammatory cytokines inflammatory chernokines NF-κB NLRP3-Ca 
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　　Background: Psoriasis is an autoimmune skin disease,in which keratinocytes play a crucial role in the pathogenesis.Semaphorin 4D(Sema4D) is an pro-inflammatory factor that has been found expressed in keratinocyte membrane in psoriatic lesion.Whether Sema4D takes part in psoriasis development and the mechanism involved is not known.
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