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5. Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIα

Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIα

来源 :上海浦东免疫化学国际生物论坛 | 被引量 : 0次 | 上传用户：tzjgy

【摘 要】

：

Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signaling and trafficking.Its kinase activity criti

【作 者】

：

Qiangjun Zhou Jiangmei Li Hang Yu Yujia Zhai Zhen Gao Yanxin Liu Xiaoyun Pang Lunfeng Zhang Klaus Schulten Fei Sun Chang Chen 

【机 构】

：

NationalLaboratoryofBiomactomolecules,InstituteofBiophysics,ChineseAcademyofSciences,Beijing100101,C

【出 处】

：

上海浦东免疫化学国际生物论坛

【发表日期】

：

2015年11期

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Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signaling and trafficking.Its kinase activity critically depends on palmitoylation of its cysteine-rich motif (-CCPCC-) and is modulated by the membrane environment.

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