Mechanistic Study on the Direct Asymmetric Vinylogous Michael Reaction of α,β-Unsaturated γ-Butyrola

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We recently developed an organocatalytic asymmetric direct vinylogous Michael addition of an α,β -unsaturated γ-butyrolactam (Nu) with chalcone (EI) catalyzed by a bifunctional thiourea-tertiary amine (Cat).
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