Processing of Ficus NGS Datasets before de novo Assembly could Make an Improvement

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户:hhxxff2009
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  We assess the impacts of different quality control methods on the Ficus NGS datasets by doing de novo assembly and evaluate certain assembly quality indicators.We focus on the relatively new area of error correction and digital normalization, and find that for low-coverage datasets, error correction may facilitate de novo assembly, while for relatively high-coverage datasets, digital normalization can reduce time and memory usage of de novo assembly, as well as enhance assembly quality.
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