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5. New Insight into Amyloid-β Fibril Growth and its InhibitionKinetic Network Analysis of Hybrid-Scale

New Insight into Amyloid-β Fibril Growth and its InhibitionKinetic Network Analysis of Hybrid-Scale

来源 :第十一届全国物理有机化学学术会议 | 被引量 : 0次 | 上传用户：wyn6098

【摘 要】

：

Formation of amyloid fibrils by self-assembly of amyloid-β peptides (Aβ) in patient brains is a hallmark of Alzheimers disease.A major step of Aβ fibril form

【作 者】

：

Wei Han 

【机 构】

：

SchoolofChemicalBiologyandBiotechnology,PekingUniversity,ShenzhenGraduateSchool,XiliTown,NanshanDist

【出 处】

：

第十一届全国物理有机化学学术会议

【发表日期】

：

2015年9期

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论文部分内容阅读

Formation of amyloid fibrils by self-assembly of amyloid-β peptides (Aβ) in patient brains is a hallmark of Alzheimers disease.A major step of Aβ fibril formation is elongation of fibrils by unstructured Aβ peptides,involving Aβ binding and structural transitions.

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