论文部分内容阅读
骨髓基质细胞脑室内移植对脑外伤后神经功能障碍的治疗作用
【机 构】
：
南通大学 南通 226001 靖江市人民医院
【出 处】
：
中国解剖学会2011年年会
【发表日期】
：
2011年1期
其他文献
Dissociation of inhibited ERK signaling from the anti-amyloidogenic action of synthetic ceramide ana
Inhibition of glycosphingolipid (GSL) synthesis reduces amyloid-beta (Aβ) production in vitro.Previous studies indicate that glucosylceramide synthase (GCS) inhibitors modulate phosphorylation of extr
Induction of endoplasmic reticulum stress and the modulation of thioredoxin-1 in formaldehyde-induce
Formaldehyde (FA), a common environmental pollutant, has toxic effects on central nervous system.The detailed mechanism of FA neurotoxicity has not been fully elucidated.In this study, we found that C
In the adult mammals, axotomy of mature neurons in the central nervous system (CNS) triggers massive cell death and failure to spontaneous axon regeneration.The relationship between axotomy-induced ne
Glutamate stimulation induces a two-phase cofilin rod formation mediated by both NMDA and non-NMDA r
Objective Cofilin is the major actin-depolymerizing factor in the CNS for regulation of actin dynamics.Neurodegenerative stimuli can induce the formation of cofilin rod, a pathological structure compo
Malignant glioma is the most common and fatal tumor in central nervous system, with the poor prognosis even with the advanced treatments.Seeking new prognostic factors and molecular targets may contri
目的 采用十四种近交系小鼠，观察并比较其在三叉神经痛模型前后对疼痛刺激敏感性的变化。方法 采用眶下神经切断手术制备三叉神经痛模型，记录手术前和手术后第14天小鼠耳廓、后爪和尾对机械痛、热痛刺激的反应。机械痛和热痛分别以von Frey毛和激光热刺激诱发。动物的行为学反应按反应强度进行量化。设假手术对照组，仅暴露同侧眶下神经但不切断。结果 (1)生理状况下，对von Frey毛机械刺激，雄性和雌性M
背景 肌细胞增强因子2D (myocyte enhancer factor-2D,MEF2D)属于转录调节因子MADS-box家族,最初被认为是肌细胞特异性DNA结合蛋白,其蛋白多结合在许多肌特异性基因的调控区域控制转录过程,发挥控制肌细胞分化过程中的基因转录功能。最近的研究表明,MEF2D还参与了多种细胞的信号传导过程,在调节细胞分化、增殖、存活和凋亡等方面发挥着重要的作用。在一些脑退行性疾病细
Objective Cerebral ischemia may contribute to the pathogenesis of Alzheimers disease (AD), however, the neuropathological relationship between these 2 disorders is largely unclear.We investigated axon
Objective Glaucoma, the second leading cause of blindness, is a neurodegenerative disease that is characterized by optic nerve degeneration resulting from apoptotic death of retinal ganglion cells (RG