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CLE peptides play role in the regulation of various types of meristems: SAM, RAM, cambium, nodule meristems, and meristem-like structures as galls and tumors.CLE peptides were divided into two groups: most of them suppress proliferation and stimulate differentiation of stem cells in SAM and RAM and belong to group A;CLE peptides functioning in cambium in favor to cell proliferation form group B.Our model is spontaneous tumors on the root of radish (Raphanus sativus L.) inbred lines.