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5. Hepatoprotective and Anti-fibrotic Effects of Permeable GCLC onHepatic Fibrosis in Rats

Hepatoprotective and Anti-fibrotic Effects of Permeable GCLC onHepatic Fibrosis in Rats

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：tianjinajun

【摘 要】

：

Background: Glutathione (GSH) is important in antioxidant defense against oxidativestress, which promotes hepatic stellate cells (HSCs) activation during hepatic fibrogenesis.The activity of glutamate

【作 者】

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Chang-Bai Liu Hu Wang Ying-Gui Yang 

【机 构】

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The Institute of Molecular Biology, China Three Gorges University

【出 处】

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中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

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2014年3期

【关键词】

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Glutathione GCLC anti-fibrosis protein transduction 

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Background: Glutathione (GSH) is important in antioxidant defense against oxidativestress, which promotes hepatic stellate cells (HSCs) activation during hepatic fibrogenesis.The activity of glutamate cysteine ligase (GCL) catalytic subunit (GCLC) is rate-limited andhas crucial role for GSH synthesis.

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