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  5. Structure Modification of Mangiferinaglycon

Structure Modification of Mangiferinaglycon

来源 :第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 | 被引量 : 0次 | 上传用户：loveme2001
【摘 要】
：
In order to find new anti-gout compounds,the structure of mangiferinaglycon is modified.Using mangiferin as starting material,a series of 3,6,7-O-trisubstituted derivatives of mangiferinaglycon,Carbon
【作 者】
：
HUANG Ping WU Song 
【机 构】
：
Key Laboratory of Biosynthesis of Natural Pharmaceutical Products,Ministry of Health of PRC,Institut
【出 处】
：
第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
【发表日期】
：
2012年8期
【关键词】
：
mangiferinaglycon modification synthesis 
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　　In order to find new anti-gout compounds,the structure of mangiferinaglycon is modified.Using mangiferin as starting material,a series of 3,6,7-O-trisubstituted derivatives of mangiferinaglycon,Carbonyl addition derivatives of mangiferinaglycon and 2-C-substituted derivatives of mangiferinaglycon were synthesized,and then theiranti-gout activities were tested in vitro with mangiferinaglyconas the control.
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