【摘 要】
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Objective To explore the effect of trimetazidine (TMZ) on the myocardial injury related to percutaneous coronary intervention (PCI) and left heart function after PCI.Methods 132 patients with unstable
【机 构】
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Beijing Anzhen Hospital Affiliated to Capital Medical University
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Objective To explore the effect of trimetazidine (TMZ) on the myocardial injury related to percutaneous coronary intervention (PCI) and left heart function after PCI.Methods 132 patients with unstable angina pectoris admitted for elective PCI were randomly assigned to 2 groups to receive or not an acute load dose of 60 mg of TMZ prior to the intervention and routine dose of 20 mg Tid after it.The frequency and the increase in the level of cTnI after successful PCI were measured before and 16-18 hours after PCI.Heart function evaluated by echocardiography and major adverse cardiac events (MACE, including death, re-infarction and target vessel revascularization) at 12 months after the procedure were also compared.
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