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Objectives To study the midterm results of simultaneous Hybrid procedure for coronary artery disease.Methods One hundred and four cases of simultaneous Hybrid procedures were performed in Fuwai Hospital between June 2007 and December 2009.Ninety-three of them were males with the mean age of 61.8±10.2 years.All the patients mainly had multivessel coronary artery disease accompanied by left anterior descending coronary artery stenosis.