Mimics of Catalase to Attenuate the Metabolism of Aerobic Glycolysis and Functions of Mitochondria i

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户:testb321
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  Hypoxia-inducible factor-1 (HIF-1) has been implicated in the regulation of genes involved in tumorigenesis, angiogenesis, glycolysis, survival, growth, invasion, metastasis, to treatment resistance.The over expression of HIF-1a is associated with advanced disease stage and poor prognosis in many common human cancers.
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