Fast Crystallization behaviors of Amorphous Pharmaceutical Solids

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户:bb314949909
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  Amorphous solids are generally more soluble and faster dissolving than their crystalline counterparts, which makes them useful for delivering poorly soluble drugs whose bioavailability is limited by their low solubility.However, amorphous drugs are thermodynamically unstable, and tend to crystallize over time due to the excess free energy.
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