BNIP3 Suppresses PINK1 Proteolytic Cleavage to Promote Mitophagy

来源 :第十四次全国医学遗传学学术会议 | 被引量 : 0次 | 上传用户：fclhp

【摘要】

：

　　Objective:Mutations in PINK1 gene cause recessive form of Parkinson's disease (PD).The PINK1 gene encodes a mitochondrial protein kinase that is processed b

【作者】

：

Tang CY Wan ZQ Wang RX Zhang TM Zeng ZT Li L Tan JQ Xue L W.Andy Tao Tang BS Zhang ZH

【机构】

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The State Key Laboratory of Medical Genetics, Xiangya Medical School, Central South University

【出处】

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第十四次全国医学遗传学学术会议

【发表日期】

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2015年期

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　　Objective:Mutations in PINK1 gene cause recessive form of Parkinson's disease (PD).The PINK1 gene encodes a mitochondrial protein kinase that is processed by mitochondrial proteases resulting in two smaller proteolytic fragments.

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BNIP3 Suppresses PINK1 Proteolytic Cleavage to Promote Mitophagy

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