【摘 要】
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The prognosis of patients with glioblastoma (GBM) remains poor, and the use of hyperfractionation or dose escalation beyond 60 Gy has not conferred any survival benefit.More recently, hypofracfionated
【机 构】
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Castle Hill Hospital UK
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The prognosis of patients with glioblastoma (GBM) remains poor, and the use of hyperfractionation or dose escalation beyond 60 Gy has not conferred any survival benefit.More recently, hypofracfionated radiotherapy (HFRT) has been employed as a novel approach for achieving dose escalation, with interesting results.We performed a systematic overview of the role and development of HFRT as a possible therapeutic strategy in patients with GBM.We searched the PubMed database for studies published since 1990 that reported on the tolerance, safety and survival outcomes after HFRT.
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