Imaging of Cisplatin by LA-ICP-MS in the model organism Caenorhabditis elegans

来源 :The 5th International Symposium on Metallomics(第五届金属组学国际研讨会) | 被引量 : 0次 | 上传用户:babaxsj
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Cisplatin is one of the most important and frequently used cytostatic drugs for the treatment of cancer.The cytostatic effect is based on binding the DNA in tumor cells by forming intra-and interstrand crosslinks.
其他文献
A series of ruthenium(Ⅱ)have been designed and investigated as potential inhibitor against metastasis of tumor.
Single cell analysis has become an important field of research in recent years reflecting the heterogeneity of cellular responses in biological systems.
A comprehensive approach that can identify and quantify selenium(Se)in selenoproteins in Se-enriched yeast was developed.
Metal nanoparticles(NPs)determination has recently attracted considerable attention because of the continuing boomof nanotechnology.In our previous work,we demonstrated that showed that TLC could achi
Iron is one of the most important inorganic nutrients for almost all plants and animals.For marine organisms,intake efficiency of Fe could be higher than those for terrestrial animals because of limit
Copper transport 1(CTR1)plays a critical role in copper uptake by cells,1 but several studies demonstrated that divalent metal transporter 1(DMT1)also transports copper in some cells and under certain
Tissue analysis using LA-ICP-MS is a powerful tool to depict the lateral resolution of trace elements within biological samples.
Since a few years Time of Flight Secondary Ion Mass Spectrometry became an important tool for the analysis of biological samples.
99m Technetium(Tc)-based complexes are widely used as contrast agents for medical diagnostics.
Transport across biological membranes is essential for arsenic absorption,distribution,metabolism and excretion.