Carbon dioxide is an ideal C1 resource,1 because it is abundant,renewable and non-toxic.However,it is thermodynamically stable,which greatly limits its application.
二氧化碳是人体代谢的产物,人每天要呼出大约1 kg 的二氧化碳,当人体血液中或大气中二氧化碳含量超过一定浓度,会引发一系列不良反应.当二氧化碳浓度在0.10-0.20%之间时,人会感觉空气污浊,并开始觉得昏昏欲睡;达到0.2-0.5%时,人会感觉头痛、嗜睡、注意力无法集中;二氧化碳含量达到0.5%以上时,可能会导致严重缺氧,造成永久性脑损伤、昏迷,甚至死亡.
In our work,a palladium/copper-catalyzed oxy-carbonation of propargylic amides by halohydrocarbons and CO2 has been developed to afford a series of functionalized oxazolidine-2,4-diones in moderate to