【摘 要】
:
Photodynamic therapy(PDT)has recently emerged as a promising noninvasive and safe treatment protocol for cancers and other non-malignant diseases.PDT involves the site-specific delivery of a photosens
【机 构】
:
Shanghai Key Laboratory of Functional Materials Chemistry,East China University of Science and Techn
【出 处】
:
第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con
论文部分内容阅读
Photodynamic therapy(PDT)has recently emerged as a promising noninvasive and safe treatment protocol for cancers and other non-malignant diseases.PDT involves the site-specific delivery of a photosensitizer and subsequent singlet oxygen production upon photo-irradiation in the presence of oxygen,leading to the irreversible cytotoxicity to the tumor tissue.
其他文献
The nano-vehicles were developed based on natural polysaccharidechitosan with different modification.Hydrophobic or hydrophilic segment with tumor microenvironmental sensitivities was grafted to chito
Conventional polymer-drug conjugates have been translated into the clinic; however,they intrinsically lack near infrared(NIR)absorbing attribute,hindering them from cancer photothermal therapy and mul
Proteins play an important role in biomedicine,ranging from basic biomedical research to diagnosis and therapy of diseases.Many of these applications depend on the ability to add new functions through
It is of high demand to develop imaging-guided smart nanoplatforms for combinational photodynamic/chemo-therapy of tumor.As depicted in Figure 1,low molecular weight heparin(LWMH)was used as the backb
Atherosclerosis,a chronic inflammatory condition,is the most manifest contributor to myocardial infarction,ischemic stroke,and atherosclerotic aneurysm.Therapeutic approaches are generally employed to
By mimicking high density lipoprotein in the central nervous system(CNS),we constructed discoidal apolipoprotein E3-reconstituted high-density lipoprotein(ApoE3-rHDL)as an efficient nanoplatform that
Functional inorganic nanoparticles have shown great potentials in diagnosing major diseases such as cancer,atherosclerosis,etc.Through past years,we have been developing versatile functional nanoparti
A water-soluble photosensitizer that demonstrates superior photodynamic therapy(PDT)efficacy,and at the same time,self-illuminates the therapeutic effect in real time is reported here,serving as an ex
Sustaining blood retention for theranostic nanoparticles is a big challenge.Various approaches have been attempted and have demonstrated some success,but limitations remain.In theory,peptides capable
We developed a series of multifunctional mixed micellar systems were developed to target to liver cancer,by means of glycyrrhetinic acid receptors abounding specifically in liver cancer cell surface,a