雷公藤多苷壳聚糖微球对小鼠实验性结肠炎的作用及机制

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：dorothyhe

【摘要】

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目的：观察雷公藤多苷(TG)壳聚糖微球对小鼠实验性结肠炎的作用及机制.方法：采用复乳-乳化交联的方法制备TG壳聚糖微球(TGM)，并检测其载药率、包封率、粒径和微球的体外释放度.90只BALB/c小鼠随机分为以下10组：对照组(N组)；DSS模型组(M组)；柳氮磺吡啶组(SASP组)；空壳聚糖微球组(C组)；TG高、中、低剂量组；TGM高、中、低剂量组.观察以下指标：①疾病活动指数(DAI)评分；

【作者】

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王石秀周南进谢勇傅颖珺

【机构】

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江西省基础医学研究院;南昌大学药学院江西省基础医学研究院

【出处】

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中国免疫学会第十届全国免疫学学术大会

【发表日期】

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2015年10期

【关键词】

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雷公藤多苷壳聚糖微球炎症性肠病 Toll样受体

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雷公藤多苷壳聚糖微球对小鼠实验性结肠炎的作用及机制

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