The optimal timing of xenon delayed postconditioning to protect against spinal cord ischemia-reperfu

来源 :第七届北京五洲心血管病研讨会 | 被引量 : 0次 | 上传用户:chunlai_zhang
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  Background our previous work had shown that xenon postconditioning at the initiation of reperfusion produced a neuroprotective effect on the spinal cord IRI in rats.Interestingly,it is reported that xenon can provide neuroprotection when applied 1 h after successful resuscitation in pigs or when administered up to at least 2 h after brain ischemia in rats.Therefore,this randomized experiment was designed to assess neuroproteetive effect of xenon delayed postconditioning on spinal cord ischemia-reperfusion injury (IRI) and determine its implement timing to provide the best protection in a rat model.
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