【摘 要】
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Objectives Endometriosis affects up to about 20% of women in their reproductive years,is associated with chronic pelvic pain,infertility,dysmenorrheal and dyspareunia.The endometriotic tissues progres
【机 构】
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Reproductive Medicine Research Centre of 6th Affiliated Hospital, Sun Yat-sen University
【出 处】
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中华医学会第十次全国妇产科学术会议
论文部分内容阅读
Objectives Endometriosis affects up to about 20% of women in their reproductive years,is associated with chronic pelvic pain,infertility,dysmenorrheal and dyspareunia.The endometriotic tissues progress with complicated internal mechanisms and have the characteristic of sustained proliferation,anti-apoptotic ability,migration and invasion.The current therapies,based on hormonal pharmacotherapy or surgery,are insufficient due to the high cost and recurrence rate.Cyclooxygenase-2 (COX-2),as a novel biomarker and molecule target,was shown to regulate survival of endometriotic cells.However,the traditional selective inhibitor,such as Celecoxib,could increase the risk of serious coronary heart diseases.
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