Treatment of inhibitors of tumor necrosis factor-a in endometriosis: Experimental study in vivo and

来源 :中华医学会第七次全国生殖医学学术会议 | 被引量 : 0次 | 上传用户:jamesshen
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Introduction To assess and compare the efficacy of anti-tumor necrosis factor therapy in eutopic endometrial stromal cells (ESCs) cultured in vitro from patients with endometriosis and its effect on endometriosis in a mouse model.Methods The mouse model of endometriosis was treated for three weeks with Tumor Necrosis Factor-a Receptor Ⅱ: IgG Fc Fusion Protein (sTNFR: Fc), rmTNF-a (Recombinant murine TNF-a), or vehicle.Growth of endometriotic lesions detected by fluorescence intensity and areas, and histology, were analyzed.
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