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Nonhost resistance is a phenomenon that enables plants to protect themselves against the majority of potential pathogens, and thus has a great potential for application in plant protection.We recently found that CfHNNI1 (for Cladosporiumfulvum host and nonhost plant necrosis inducer 1) is an inducer of plant hypersensitive response (HR) and nonhost resistance.In this study, its functional mechanism was analyzed.