THE EFFECT OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE INHIBITOR CYCLOSPORIN A ON RAT HEART PROTEC

来源 :第七届亚洲体外循环学术会议暨第三届全国体外循环学术会议 | 被引量 : 0次 | 上传用户：wutsc

【摘要】

：

【作者】

：

LIN Ru YU Jiangen

【机构】

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Department of Thoracic and Cardiovascular surgery,Affiliated Children's Hospital,School of Medicine

【出处】

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第七届亚洲体外循环学术会议暨第三届全国体外循环学术会议

【发表日期】

：

2007年12期

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　　Objective:To observe the cardio protective effect of hyperkalemic cardioplegic solution enriched with mitochondrial permeability transition pore inhibitor cyclosporin A on rat heart subjected ischemia.Methods:Twenty-seven adult male Sprague-Dawley rat hearts were randomly divided into 3 groups (9 rats in each group):St.Thomas group; 0.2μmol/L cyclosporin A + St.Thomas groups; 0.2μmol/L cyclosporin A +20μmol/L atractyloside + St.Thomas group.

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THE EFFECT OF MITOCHONDRIAL PERMEABILITY TRANSITION PORE INHIBITOR CYCLOSPORIN A ON RAT HEART PROTEC

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