The engineered ascorbate peroxidase(APEX2)has emerged as a powerful system to provide proteomic maps of proteins in numerous subcellular compartments[1].
The E3 ligase adaptor SPOP,overexpressed and dislocated into the cytoplasm in all ccRCC,serves as a regulatory hub to promote kidney cancer through the ubiquitination and degradation of multiple downs
Photosensitizers are essential in the field of photodynamic therapy(PDT)for cancer.Transition-metal complexes are widely explored as photosensitizers due to their high photostability,large stokes shif