β2 structure of BK channel based on the pairing mode of cysteines

来源 :10th IST Asia Pacific Congress on Animal , Plant and Microbi | 被引量 : 0次 | 上传用户:xxq0108
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The extemal loop of β2 plays an important role in regulating the gating and pharmacological properties of large conductance Ca2+-activated K+ (BK) channels.The corresponding structural information of β2 loop is extremely critical for understanding its regulating mechanism.However,its eight cysteines make it difficult to obtain the exact structure of β2.
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