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Objective:To evaluate the prognostic impact of human leukocyte antigen (HLA) alleles and haplotypes in patients with nasopharyngeal carcinoma from a Han population in Xinjiang.Methods:A retrospective study was conducted to phenotype the HLA-A,HLA-B alleles and HLA-A,-B haplotypes and correlated these data to clinical and pathological parameters in a cohort of 117 NPC patients from a Han population in Xinjiang.