低出生体重追赶生长关键期运动干预的机制

来源 :中华医学会第四届糖尿病及性腺疾病学术会议 | 被引量 : 0次 | 上传用户:vickyfucandy
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目的 研究低出生体重和出生后追赶生长在生长的关键时期给予运动干预后是否可以通过改善线粒体功能缓解相关的代谢性疾病.方法 低出生体重小鼠模型通过对C57BL/6J孕鼠分娩前一周限制饮食获得,所有雄性仔鼠均母乳喂养3周,第4周按随机分组方法分8组:正常出生体重正常饮食组,正常出生体重高脂饮食组,正常出生体重高脂饮食运动组,正常出生体重高脂饮食mitoQ(线粒体靶向抗氧化剂)组,低出生体重正常饮食组,低出生体重高脂饮食组,低出生体重高脂饮食运动组,低出生体重高脂饮食mitoQ组.
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