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5. Coordination-driven Assembly of Catechol-modified Chitosan for Kidney-specific Delivery of Salvianol

Coordination-driven Assembly of Catechol-modified Chitosan for Kidney-specific Delivery of Salvianol

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：wyattwong

【摘 要】

：

Kidney-specific delivery is critically important for treatment of renal fibrosis with drugs such as Salvianolic acid B(Sal B).[1,2] In this study,we report a kidney-specific nanocomplex formed by coor

【作 者】

：

Jing Li CuitingZhang KaiKaiWang David Oupicky MinjieSun 

【机 构】

：

State Key Laboratory of Natural Medicines and Department of Pharmaceutics,China Pharmaceutical Unive

【出 处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

【关键词】

：

kindey-specific delivery coordination nanocomplex renal fibrosis salvianolic aci 

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　　Kidney-specific delivery is critically important for treatment of renal fibrosis with drugs such as Salvianolic acid B(Sal B).[1,2] In this study,we report a kidney-specific nanocomplex formed by coordination-driven assembly of catechol-modified low molecular weight chitosan(HCA-Chi),calcium ions and Sal B(Scheme 1).

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