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Background: Porcine circovirus type 2 (PCV2) infection alone cant cause the herd serious clinical symptoms usually, however, when it co-infection with other causative agents will trigger post-weaning multisystemic wasting syndrome.Vaccination is one of the effective measures to control the disease, and this strategy has been widely adopted and achieved successfully.Next, we meet the problem that how to evaluate the immune efficiency PCV2 vaccine.Several commercial PCV2-ELISA antibody detection kits are available, but the difference in brand leads to the diversity of quality possibly.