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5. Design, synthesis, biological evaluation of 4-isochromanone hybrids as dual binding site inhibitors

Design, synthesis, biological evaluation of 4-isochromanone hybrids as dual binding site inhibitors

来源 :2016年长三角药物化学研讨会 | 被引量 : 0次 | 上传用户：book_008

【摘 要】

：

The reduction of Acetylcholinesterase (AChE) activity in the central nervous system (CN) is one of the major aetiologies of Alzheimers disease (AD),and AChE inhibitors become the common drugs in the c

【作 者】

：

Zheng Wu Jia Wang Chaolei Wang Jie Liu Jinyi Xu 

【机 构】

：

Department of Medicinal Chemistry, China Pharmaceutical University;State Key Laboratory of Natural M

【出 处】

：

2016年长三角药物化学研讨会

【发表日期】

：

2016年11期

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　　The reduction of Acetylcholinesterase (AChE) activity in the central nervous system (CN) is one of the major aetiologies of Alzheimers disease (AD),and AChE inhibitors become the common drugs in the current treatment of AD.

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