【摘 要】
:
Type 2 diabetes has become a global pandemic and imposes a growing burden to people and society.Although multiple treatment options are available,there remain unmet medical needs for better and safer
【机 构】
:
Novo Nordisk Research Centre China Building #2, 20 Life Science Park Road, Changping District, Beiji
论文部分内容阅读
Type 2 diabetes has become a global pandemic and imposes a growing burden to people and society.Although multiple treatment options are available,there remain unmet medical needs for better and safer therapies.
其他文献
目的:观察猪尾式探针联合非外露环形硅胶支撑管术治疗陈旧性泪小管断裂的效果。方法:对15例(15眼)陈旧性泪小管断裂患者实施二期手术治疗,术中借助猪尾式探针找到泪小管的鼻侧断端,置入环形硅胶支撑管,置管6个月,观察疗效。
视觉训练已有一百多年的历史,传统的视觉训练主要针对眼位的偏斜和视力的提升。正常地阅读、学习、运动和生活不仅需要正常的视力,更有赖于完整的视觉技能,包括眼球运动控制、看远时双眼同时聚焦、看远时持续聚焦、看近时同时聚焦、看近时持续聚焦、看远时双眼正位、看远时维持正位、看近时双眼正位、看近时维持正位、中心视力(视力)、周边视觉、深度觉、颜色知觉、粗糙的视觉运动、精细的视觉运动、视知觉整合。除眼部的异常或
As increased thermogenesis in white adipose tissue (WAT),or browning,promotes energy expenditure,significant efforts have been invested to determine the molecular players involved in this process.
Ischemic heart disease is the leading cause of death worldwide,with myocardial infarction as a common presentation.The most effective approach to mitigate cardiac damage of myocardial infarction is ti
The master regulator of adipocyte biology,nuclear receptor PPARγ plays pivotal roles in the pathophysiology of obesity and diabetes.PPAR γ.is a key target for insulin sensitization;however,its thiazol
Oxidative stress derived from various etiologies including environmental exposure,life-style changes,and systemic inflammation,can damage pancreatic β-cells,leading to the deficiency of insulin as typ
Obesity has emerged as a major threat to public health.Essentially a disorder of energy balance,obesity occurs when energy intake exceeds expenditure.Our previous work led to the isolation of a new ty
Facing the grand challenges of biological complexity,researchers have developed the systems biologyapproaches for integrating data derived from genomics,proteomics and metabolomics and other omics,int
It remains controversial as to whether adiponectin exerts anti-or pro-thermogenic effects.Here,we show that basal,acute,and chronic cold-induced energy expenditure as well as the browning effect are e