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5. 甾体药物中间体6-亚甲基单酯“一锅法”合成及结构表征

甾体药物中间体6-亚甲基单酯“一锅法”合成及结构表征

来源 :中国化学会第九届全国有机化学学术会议 | 被引量 : 0次 | 上传用户：chendegeng1234

【摘 要】

：

6-亚甲基单酯是合成一些终端原料药如甲地孕酮、安宫黄体酮、可的松醋酸酯、己酸孕酮等甾体激素类药物的关键中间体[1],化学名称：17α-乙酰氧基-6-亚甲基孕甾-4-烯-3,20-二酮(17α-Acetyloxy-6-methyleneprogn-4-ene-3,20-dione)。

【作 者】

：

田光辉 刘存芳 杨亮 葛红光 翟振琪 

【机 构】

：

陕西理工学院化学与环境科学学院 陕西汉中,723001 城固县振华生物科技有限责任公司 陕西城固,

【出 处】

：

中国化学会第九届全国有机化学学术会议

【发表日期】

：

2015年7期

【关键词】

：

一锅法 合成 6-亚甲基单酯 结构表征 

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论文部分内容阅读

　　6-亚甲基单酯是合成一些终端原料药如甲地孕酮、安宫黄体酮、可的松醋酸酯、己酸孕酮等甾体激素类药物的关键中间体[1],化学名称：17α-乙酰氧基-6-亚甲基孕甾-4-烯-3,20-二酮(17α-Acetyloxy-6-methyleneprogn-4-ene-3,20-dione)。

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