The Role of MicroRNA in Adaptation of Microglia and Macrophages to CNS Microenvironment

来源 :2013第四届国际神经科技大会 | 被引量 : 0次 | 上传用户:guweichen
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Inflammation in the central nervous system (CNS) is a complex process with a high social and economic irnpact worldwide.Currently there is no effective therapy for prevention and treatment of CNS inflammation that accompany many neurodegenerative diseases such as multiple sclerosis (MS) or Alzheimers disease.In this talk I will give an example of regulation of inflammation in the CNS by microglia.
其他文献
Background: Cognition enhancement has become a hot topic and is currently arousing intense public and scientific debate.While definitions vary, cognition enhancement can be defined as improved ability
会议
Common metabolic alterations are associated with the progression of a growing number of neurodegenerative disorders, characterized by different ethiopatogenesis.In the case of adrenoleukodystrophy (X-
会议
The modem development of technology yields to produce three dimensions images of biological objects with high resolution.At the present study a new method for quantitative estimation of metabolite con
会议
Creutzfeldt-Jakob disease (CJD) is a group of rare diseases that can be sporadic, genetic or infectiously acquired, but is invariably fatal in all of its forms.Attempted pharmacotherapies that have be
会议
Schizophrenia is characterized by disturbances of perception, emotion, social functioning and cognition.Studies suggest that genetics, early environment, neurobiology, psychological and social process
会议
先天免疫细胞的各种模式识别受体(PRRS)识别病原相关分子模式(PAMPS)是抵御病原体入侵宿主的第一道防线。文献报道,在几种神经退行性疾病模型中,小胶质细胞上的模式识别受体RAGE参与脑内免疫反应并影响神经存活。本工作阐明了小胶质细胞的细胞表面受体,整合素Mac-l (macrophage antigen complex l),发挥模式识别受体功能,识别内源性警报素(alarmins)和入侵病原
会议
Duchenne muscular dystrophy (DMD) is an X-linked inherited muscle disorder with progress muscle fiber degeneration and replaced by connective and fatty tissues.The patients will loss ambulatory abilit
会议
It is generally believed that synapse-to-nucleus communication plays an important role for longterm memory formation.However, the control of activity-dependent gene expression by synaptic signals is s
会议
The development of severe metabolic acidosis in seriously ill patients is often accompanied by multi-organ dysfunction and an increase in morbidity and mortality.Current acid-base correction with sodi
会议
Experimental studies reveal that the pathogenesis of neurogenic inflammation involves an activation of spinal cord GABAergicinterneuronal circuits where action potentials are generated and then propag
会议