Multiple dimensional feature space for protein interface residue prediction

来源 :第七届全国生物信息学与系统生物学学术大会 | 被引量 : 0次 | 上传用户:daweinihao
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Protein-protein interacts through specific interface residues to execute biological functions.Correctly understanding the mechanisms of interface recognition and predicting the interface residues are important for many aspects of life science studies.Here,we report a novel architecture to study and predict protein interface residues.In our method,a multiple dimensional feature space was built on some meaningful features.Then we grided the space and put all the surface residues into the grids according to their feature values.
其他文献
Horizontal transfer (HT) is the passage of genetic material between non-mating species.Transposable elements (TEs) have inherent ability to mobilize and proliferate within genomes,and over 200 cases o
Pseudogenes,which have long been described as "fossils",play a very important role in eukaryotic genomes.Recently,studies on the so called "junk gene" have attracted more attention.Far from being sile
Long non-coding RNAs (LncRNAs) are typically defined as transcripts longer than 200 nucleotides,participate in transcriptional,epigenetic,or post-transcriptional regulation of gene expression[1].Latel
Non-coding RNA (ncRNA) genes make transcripts as same as the encoding genes,and ncRNAs directly function as RNAs rather than serve as blueprints for proteins.As the function of ncRNA is closely relate
Advances in transcriptomics has led to the discovery of a large number of long intergenic non-coding RNAs (lincRNAs),which are now recognized as important regulators of diverse cellular processes.Alth
Long intergenic non-coding RNAs (lincRNAs) may play widespread roles in biological processes,however,a systematic examination of the functions of lincRNAs in the biological responses of rice to phosph
会议
Among the identified thousands of circular RNAs (circRNA) in humans and animals,CDRlas (also known as CiRS-7) was recently demonstrated to act as a powerful miR-7 sponge.Here,we find CDR1as is downreg
Circular RNA are a new class of noncoding RNA in numerous species.They are relatively stable in cytoplasm thank to their loop structure.They are believed to have multiple potential functions,such as m
Acute myocardial infarction (AMI) is a kind of common disease of cardiovascular disease.During the course of AMI morbidity,it will lead to potential complication from the disease,like atrial fibrillat
Various types of mutation and editing (M/E) events in miRNAs can change the stabilities of pre-miRNAs and/or complementarities between miRNAs and their targets.Small RNA (sRNA) high-throughput sequenc