【摘 要】
：
Through a ruthenium-catalyzed selective hydrogen transfer coupling reaction,a novel straightforward synthesis of 1,2,3,4-tetrahydronaphthyridines(THNADs) from o
【机 构】
：
SchoolofChemistry&ChemicalEngineering,SouthChinaUniversityofTechnology,Guangzhou510640,P.R.China
【出 处】
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第五届岭南有机化学论坛暨华南理工大学-兰州大学有机化学双边论坛
论文部分内容阅读
Through a ruthenium-catalyzed selective hydrogen transfer coupling reaction,a novel straightforward synthesis of 1,2,3,4-tetrahydronaphthyridines(THNADs) from o-aminopyridyl methanols and alcohols has been developed.The synthetic protocol proceeds in an atom-and step-economic fashion together with the advantages of operational simplicity,broad substrate scope,production of water as the only byproduct,and no need for external reducing reagents such as high pressure H2 gas,offering a highly practical approach to access this type of structurally unique products.
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