【摘 要】
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Context TGF-b1 regulates bone metabolism,mediating bone turnover during postmenopause.Sclerostin negatively regulates Wnt-signaling pathway,also being important for postmenopausal bone loss.Little is
【机 构】
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Research Section of Geriatric Metabolic Bone Disease,Shanghai Geriatric Institute,Department of Oste
【出 处】
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中华医学会第七次骨质疏松和骨矿盐疾病中青年学术会议
论文部分内容阅读
Context TGF-b1 regulates bone metabolism,mediating bone turnover during postmenopause.Sclerostin negatively regulates Wnt-signaling pathway,also being important for postmenopausal bone loss.Little is known about the correlation between serum TGF-b1 and Sclerostin during menopause.Objective The aim of this study was to observe the changes of serum TGF-b1 and Sclerostin during menopause,and evaluate the relationships between them.Design,Setting,and Participants We conducted a cross-sectional observational study of healthy pre-and postmenopausal women.Intervention(s):There were no interventions.
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Context TGF-b1 regulates bone metabolism,mediating bone turnover during postmenopause.Sclerostin negatively regulates Wnt-signaling pathway,also being important for postmenopausal bone loss.Little is