【摘 要】
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Background To investigate the level of IL-18 in patients underwent coronary percutaneous coronary intervention (PCI)before and after operation and to explore IL-18 value in predicting of contrast-indu
【机 构】
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Department of Cardiology,Affiliated Hospital of Xuzhou Medical College,Xuzhou,Jiangsu,China
【出 处】
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第十二届中国介入心脏病学大会(CIT2014)
论文部分内容阅读
Background To investigate the level of IL-18 in patients underwent coronary percutaneous coronary intervention (PCI)before and after operation and to explore IL-18 value in predicting of contrast-induced nephropathy (CIN).Methods A total of 180 patients underwent PCI were randomly divided into three groups: the sodium chloride group (the control group consisted of 60 cases),the vitamin C group (the treated group consisted of 60 cases),and the vitamin C and Danhong group (the other treated group consisted of 60 cases).The sodium chloride group were given 0.9％ sodium chloride with the speed of 1 ml·kg-1 ·h-1) from 6h before operation to 12 hours after operation;vitamin C group were given vitamin C 3.0 g by intravenous infusion 2-4 hours before operation and oral vitamin C 1.0 g respectively on following 2 days after operation on the basis of the sodium chloride group treatment,the total dose of the vitamin C was 5 g;the vitamin C and Danhong group were given additional 40 ml Danhong injection in 0.9％ sodium chloride 1 hour before PCI on the basis of the Vitamin C group treatment.The renal function of all patients were accessed before and 2-3 days after operation.The estimated GFR was calculated using the modified modification of diet in renal disease equation for Chinese patients.And 15 ml urine was collected before and 2,6,12,24,48 hours after operation.
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