【摘 要】
：
Background Biodegradable polymer drug-eluting stents (BPDES) have been developed to address the risk of stent thrombosis.The EXCEL stent (JW Medical Systems,Weihai,China) features an abluminal PLA dru
【机 构】
：
Fu Wai Hospital,National Center for Cardiovascular Diseases,Beijing 100037,China
【出 处】
：
第十二届中国介入心脏病学大会(CIT2014)
论文部分内容阅读
Background Biodegradable polymer drug-eluting stents (BPDES) have been developed to address the risk of stent thrombosis.The EXCEL stent (JW Medical Systems,Weihai,China) features an abluminal PLA drug carrier that enables a 6-9 months 100％ drug release in vivo.The BuMA stent (Sino Medical,Tianjin,China) features an electro-grafting (eG) base layer and a PLGA drug carrier.The eG layer secures adhesion of the biodegradable PLGA coating as a result of the interdigitation,and the PLGA coating ensures 100％ drug release within 30 days.We aimed to use optical coherence tomography (OCT) to compare 3-month neointimal formation between the two BPDES,both of which have a stainless steel platform and release sirolimus,but with different biodegradable coating designs.
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