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  5. EphB2/EphrinB1 signaling improves bone mass of OVX mice through increasing osteogenesis and inhibiti

EphB2/EphrinB1 signaling improves bone mass of OVX mice through increasing osteogenesis and inhibiti

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户：Melanzpl1
【摘 要】
：
Background: The loss of estrogen at menopause causes the increasing bone-resorbing activity of osteoclasts to outpace the bone-forming activity of osteoblasts, always leading to the occurrence of post
【作 者】
：
Liu Yang Qizhen He Qiyue Shi Jian Liu Zhuojing Luo 
【机 构】
：
Institute of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China
【出 处】
：
第七届国际骨质疏松及骨矿盐疾病学术会议
【发表日期】
：
2014年3期
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Background: The loss of estrogen at menopause causes the increasing bone-resorbing activity of osteoclasts to outpace the bone-forming activity of osteoblasts, always leading to the occurrence of postmenopausal osteoporosis (PMOP).Recently the Ephrin/Eph family of receptor tyrosine kinases has been shown to play an important role in regulating bone homeostasis.However the function of Ephrin/Eph in estrogendeficient osteoporosis has not been mentioned.
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