Jaridonin, a novel anticancer drug, induced human gastric cancer cell line MGC-803 autophagy and Its

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：cherry_20050901

【摘要】

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【作者】

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Xu-yao ZHANG Xiao-jing SHI Dong CHEN Ran WANG Hong-min LIU

【机构】

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School of Pharmaceutical Sciences,New Drug Research & Development Center,Zhengzhou University,Zhengz

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

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ent-kaurene diterpenoid compound anticancer autophagy molecular mechanism

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Aim: Jaridonir, a novel ent-kaurane diterpenoid compound from Isodon Rubescens in our laboratory.We designed the current study to determine the effects of Jaridonin on human gastric cancer line MGC-803 autophagy and its possible mechanisms.Methods: After treatment by Jaridonin for 24 h, the effect of Jaridonin on the MGC-803 cell viability was examined using MTT assay.

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Jaridonin, a novel anticancer drug, induced human gastric cancer cell line MGC-803 autophagy and Its

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