Control of lipid homeostasis by CIDE proteins

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：dephibase

【摘要】

：

Lipid homeostasis is crucial in maintaining normal physiological function and its dysregulation results in the development of obesity,diabetes,cardiovascular disease and cancer.Lipid droplets(LDs)are

【作者】

：

Peng Li

【机构】

：

School of Life Sciences,Tsinghua University

【出处】

：

中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Lipid homeostasis is crucial in maintaining normal physiological function and its dysregulation results in the development of obesity,diabetes,cardiovascular disease and cancer.Lipid droplets(LDs)are responsible for lipid storage and intracellular lipid homeostasis.

其他文献

Tracking copy number variations of tumor suppressor mutations induced in CRISPR/Cas9-mediated mouse

CRISPR/Cas9-based targeted somatic multiplex-mutagenesis is a powerful tool for development of mouse liver cancer models.

会议

CRISPR/Cas9somatic multiplex-mutagenesisliver tumor heterogeneityextrachromos

基于结构变异的香猪抗病基因的资源挖掘

香猪作为贵州地方特色猪种，以肉质香嫩、基因纯合、富含微量元素、纯净无污染等独特优点而著称，具有良好的经济效应。与此同时，香猪适应性好、抗病力强、耐粗饲，故而挖掘香猪的抗病基因具有重要的意义。基因组水平的结构变异能够影响基因的功能，以致影响个体表型性状，在物种进化中也起着重要作用。

会议

贵州地方猪种结构变异抗病基因

Reconstitution of human eukaryotic translation initiation factor 3 using a ribozyme-mediated polycis

Eukaryotic initiation factor 3(eIF3)is the largest factor involved in mRNA translation initiation,consisting of 13 different subunits.

会议

translation initiationeIF3polycistronic

PES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERα/ERβ

Estrogen has been suggested to play a role in the occurrence and development of papillary thyroid cancer(PTC).The balance and the ratio between ERα and ERβ protein are crucial in determining the effec

会议

PES1ERαERβpapillary thyroid cancer

Mutations at Cys392 and Asp393 influence the FAD Binding and the Formation and Stability of the Radi

Plant cryptochromes are blue-light receptors that regulate the light-dependent growth,development and circadian rhythm in plants.An FAD cofactor is bound in the photolyase homology region(PHR)of plant

会议

plant cryptochromeFADphotoreductionmutationradical

The action of DNA-binding ligands with unusual DNA structures:implications for therapy and diagnosis

会议

Rational Design of a Broad-spectrum Vaccine by Compromising Viral-Type Specificity--a Type-Cross Hum

会议

砷结合蛋白的全局性预测方法与功能分析

砷和砷化物是最为常见的环境毒物，被许多国际组织列为头等有害物质。长期的砷和砷化物暴露会对人体产生急性或者慢性的毒性，可以导致皮肤病损并且增加心血管系统、呼吸系统、肠胃系统、生殖系统的恶性疾病风险。但是砷化物却对多种恶性疾病有着惊人的治疗效果，比如三氧化二砷和全反式维甲酸的联合使用可以使早幼粒白血病患者的五年生存率提高到85％至90％。

会议

砷结合蛋白全局性预测方法信号转导通路泛素化修饰

Identification and Analysis of Gastrodia elata miRNA and Preliminary Studies on Its Cross-kingdom Re

Gastrodia elata is one of precious Chinese herbal medicines,which has a variety of functions such as anticonvulsant effect,neuroprotection,anti-inflammatory and immune regulation.MicroRNAs(miRNAs)are

会议

Gastrodia elata microRNAcross-kingdom regulationNF-κB signaling pathway

Cyclin D1 is a Mediator of Gastrointestinal Stromal Tumor KIT-independence

Purpose: Oncogenic KIT or PDGFRA tyrosine kinase mutations are compelling therapeutic targets in most gastrointestinal stromal tumors(GISTs),and the KIT/PDGFRA inhibitor,imatinib,is therefore standard

会议

cyclin D1PRKCQJUNKITHippo pathwaygastrointestinal neoplasm

Control of lipid homeostasis by CIDE proteins

与本文相关的学术论文