【摘 要】
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Objective:To compare and further evaluate FA and EAR measures of diffusion anisotropy in children of idiopathic generalized epilepsy (IGE). Materials and Methods:Diffusion tensor images were obtained
【机 构】
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Department of Radiology,Xin Hua Hospital Affiliated to Shanghai Jiaotong University School of Medici
【出 处】
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中华放射学学术大会2016、中华医学会第23次全国放射学学术大会暨中华医学会第24次全国影像技术学术大会
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Objective:To compare and further evaluate FA and EAR measures of diffusion anisotropy in children of idiopathic generalized epilepsy (IGE). Materials and Methods:Diffusion tensor images were obtained from three IGE groups.Fifteen children included in group 1 with bilateral interictal epileptiform discharges (IED) by EEG,9 children with left/right IED in group 2 and group 3 respectively.Three age- and sex- matched children were recruited as normal control (NC) groups.FA and EAR were estimated through voxel-based analyses.A 2-sample t-test for group analysis compared between the three IGE and NC groups.Results:In group 1,both FA and EAR reductions were in left frontal and temporal lobes of the white matter (WM),while EAR also revealed reductions in the right cerebrum of the WM.In group 2,the reductions of FA and EAR were in the left fusiform and occipital lobe of the WM.EAR also revealed differences in the left frontal lobe.Both FA and EAR revealed differences were in the WM of the left cerebrum in group 3.EAR also revealed differences in the temporal lobe.Conclusions:EAR detected more localized abnormalities and is more sensitive to WM alteration than FA in children with IGE.
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