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Renewable energy from lignocellulosic biomass has been deemed an alternative to depleting fossil fuels.In order to improve this technology,we aim to develop robust mathematical models for the enzymatic lignocellulose degradation process.By analyzing 96 groups of previously published and newly obtained lignocellulose saccharification results and fitting them to Weibull distribution,we discovered Weibull statistics can accurately predict lignocellulose saccharification data,regardless the type of substrates,enzymes and saccharification conditions.