论文部分内容阅读
Retinal microglia behavior in mouse oxygen-induced retinopathy model:quantitation and distribution
【机 构】
：
Department of Ophthalmology,Li Ka Shing Faculty of Medicine,The University of Hong Kong,Hong Kong,Ch
【出 处】
：
The 6th FAONS Congress and 11th Biennial Conference of CNS(第
【发表日期】
：
2015年3期
其他文献
Glutamate(Glu),the most important excitatory neurotransmitter in the central nervous system(CNS),mediates synaptic plasticity,learning and memory.Astrocytes remove Glu from extracellular fluid to prot
Objective Ischemic stroke is one of the leading causes of mortality and significant disability,which incidence of Ischemic stroke accounts for 60-80%of all the stroke patients.The neurogenesis gives u
Cerebral ischemia can cause acute damage to neurons,but how the microglia are affected during ischemia is poorly understood.In this study we used bilateral common carotid artery ligation(BCAL)model to
CD34 stained microvascular density of pituitary adenoma for evaluation of its invasiveness:a systema
Background CD34 is a transmembrane phosphoglycoprotein,first identified on hematopoietic stem and progenitor cells.CD34 is well known as an endothelial marker,and it gives positive staining in physiol
GDNF(glial cell-line derived neurotrophic factor,)是一种分泌性蛋白,可促进胶质瘤细胞增殖 。 GDNF 对胶质瘤细胞的增殖作用须通过跨膜信息传递,即受体的介导才能实现 。
Entinostat-attenuated DNA repair protein MGMT plays a crucially synergistic role in temozolomide-inj
胶质细胞系源性神经营养因子(glial cell line-derived neurotrophic factor,GDNF)基因在胶质瘤细胞中异常高转录与其启动子Ⅱ区甲基化修饰变化有关,但其具体机制不清。有研究表明,GDNF 基因启动子Ⅱ区存在转录因子CREB 的2 个结合位点(分别位于增强子区和沉默子区),并且它们发生了不同程度的甲基化修饰改变。