Hepatic ZBTB20 regulates lipid metabolism and insulin sensitivity

来源 :第八届湘雅国际糖尿病免疫学论坛 | 被引量 : 0次 | 上传用户:zhoumi2008
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Hepatic lipogenesis is regulated by dietary carbohydrates, and have a critical role in the development of hepatic steatosis and insulin resistance.Here we show that the novel zinc finger protein ZBTB20 in liver regulates lipid metabolism and insulin sensitivity.ZBTB20 nuclear translocation was highly regulated by nutritional status in hepatocytes.
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